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In the wake of SHIELD's collapse, an ancient primordial evil has been awakened beneath the streets of New York, and with it, something equally evil has awakened in the most Wicked of Webslingers - VENOM! Still a Lethal Protector of the innocents in New York, this never-before-seen threat could force Venom to relinquish everything it holds dear - including Eddie Brock! Join two of the hottest creators in comics today, Donny Cates and Ryan Stegman, for a Venom adventure a thousand years in the making! Rated T+

Though it requires a living host in order to survive, the Venom symbiote has been shown to be adept at fending for itself independent of a host. The Symbiote is capable of shapeshifting abilities, including the ability to form spikes or expand its size,[90] as well as mimic the appearance of other humanoids after it has obtained a host. The organism can additionally use its shape-shifting abilities to conceal itself by altering its coloration or by becoming completely invisible. It also contains a small "dimensional aperture", allowing its hosts to carry items without adding mass to the costume. The Symbiote also exhibits telepathic abilities, primarily when it needs to communicate with its host.[citation needed]

Because of its contact with Spider-Man, the Symbiote grants all of its subsequent hosts that hero's powers and cannot be detected by his spider-sense. As Spider-Man's fighting style is partly dependent on his spider-sense, his effectiveness was somewhat hampered when he battled Eddie Brock. Retaining its memory from the time it was bonded with Spider-Man, Venom is also capable of producing webbing similar to Spider-Man's own variety created from itself.

The Symbiote greatly enhances the physical strength of those it bonds with. Its hosts experience a vastly larger size and musculature. The Symbiote displays non-human teeth, which are very sharp, and commonly protrudes a long tongue from its mouth. Venom is depicted as being physically much bigger than Spider-Man, as well as having more brute strength.